World’s oldest RNA extracted from Ice Age woolly mammoth

Scientists have made a groundbreaking discovery in the field of paleogenetics, extracting and sequencing RNA from the frozen remains of an Ice Age woolly mammoth. The ancient creature, known as Yuka, was frozen for approximately 40,000 years before its remains were discovered by local hunters in 2010. What's remarkable is that researchers were able to recover intact RNA fragments from Yuka's tissue, providing a window into the biology of an extinct species.

The team at Stockholm University carefully ground up bits of muscle and other tissue from Yuka and nine other woolly mammoths, then used special chemical treatments to extract the RNA. This was a major challenge, as most previous attempts to extract RNA from ancient specimens had failed or been contaminated. However, the researchers were able to overcome these hurdles using adapted methods for handling fragile molecules.

Studying Yuka's RNA revealed valuable insights into its final moments of life. Scientists discovered that its muscles were tensing and cells were signaling distress in the seconds before death – a crucial finding that sheds light on the biology of an extinct species. This is particularly significant, as studying DNA alone can provide only information about an organism's evolutionary history.

The breakthrough has major implications for understanding ancient genomes and potentially shedding new light on the evolution of life on Earth. Researchers hope to apply this technique to other long-extinct species, such as Tasmanian tigers and woolly mammoths, in order to explore gene expression differences between extinct and living species. The method could also be used to study the biology of currently endangered species, providing new insights into their evolution and conservation.

This groundbreaking discovery opens a new window into lost worlds, offering scientists clues that could help protect threatened species from extinction. As paleogenetic research continues to advance, we can expect even more exciting breakthroughs in our understanding of life on Earth – past and present.
 
OMG u guys this is mind blown!!! extracting RNA from 40k yrs old woolly mammoth is like something outta a sci-fi movie 🤖💥 think about all the info they'll get from these frozen tissues... muscle tension, distress signals, it's all there! 👀 they're gonna take this tech and apply it to other extinct species and endangered ones too, imagine being able to study tigers in Tasmanian wilderness again 🐯🌳 or even bring back some kind of ancient DNA info for conservation efforts 🌟
 
OMG!!! 🤯 this is so cool!! they actually got RNA from 40k yrs old mammoth?? that's like science magic! 🧙‍♂️ i wonder what other secrets yuka was hiding in her frozen body? scientists are like detectives, trying to solve the mystery of life and death. this discovery is huge, can't wait to see more research on tasmanian tigers and endangered species too!! 💡 conservation efforts just got a whole lot stronger
 
I'm freaking out over this mammoth news lol 🤯!! I mean, think about it... 40k years ago Yuka was chillin' like a villain and then BAM! She freezes to death 🥶 and her body becomes a time capsule for us to learn from 🕰️. And can you believe they were able to extract RNA from those ancient remains? It's like science magic ✨. The fact that they found out what was going on in Yuka's cells right before she died is wild... it's like we're getting a glimpse into her final moments of life 😱. I'm curious to see if they can apply this tech to other extinct species and endangered ones too, maybe we'll learn more about how our planet affects the creatures that live here 🌎. This discovery is giving me goosebumps 💀!
 
OMG u guys this is like literally the coolest thing ever! 🤯 Scientists managed 2 extract RNA from a 40k yr old woolly mammoth & now they know what was goin thru its mind 2 mins b4 it died 😲 Like, can u even imagine? They're talkin about applyin this tech 2 other extint species & helpin endangered ones b4 they become extinct 🌟 It's like we're gettin closer 2 bein able 2 talk 2 our ancient friends 🤗
 
I gotta say, this is like mind blown 🤯! Scientists have finally figured out how to get RNA from those ancient mammoths, it's crazy! I mean, 40k years old and still got intact RNA, that's wild 😲. This opens up so many possibilities for learning about extinct species, it's awesome. But at the same time, it's also super sobering 🤕 thinking about all the species we've lost forever. We gotta use this tech to learn from them and help preserve what's left, you know? It's like we're getting a second chance to understand our past and maybe even save some species that are still hanging on by a thread 💔.
 
I'm both hyped and skeptical about this whole thing 🤔💡 First off, 40k years is a looong time to be stuck in ice, what's the chance Yuka just magically woke up one day? 😂 But seriously, getting RNA from ancient specimens is like winning the genetic lottery 🎉. The fact that they were able to extract it and study its DNA means we're learning more about these incredible creatures than we ever thought possible.

But it also makes me wonder, what's the real significance here? I mean, knowing how Yuka's muscles tensed before death is cool and all, but is it really gonna make a huge difference in our understanding of conservation efforts? 🤷‍♀️ We need to be careful not to get too caught up in the excitement of this discovery and forget about the bigger picture. Still, I gotta say, it's definitely an awesome step forward for science 💪🌟
 
can you imagine being able to see the world through the eyes of a 40k year old woolly mammoth? like, what was its daily life like? was it living in a forest or tundra? 🐘🌿 i think this discovery is not just about the science itself but also about how it makes us feel connected to our past and each other as humans. we're basically able to learn from an extinct species, which is wild (pun intended) 🤯
 
😊 So they finally cracked the code on extracting RNA from ancient mammoths! I mean, 40k years is a looong time, but I guess that's what happens when you're frozen for millennia 😂. It's wild to think about all the secrets those creatures must have held within their cells. The fact that they were able to recover intact fragments is just mind-blowing - I'm sure it wasn't easy, but now we can finally see how those woolly mammoths were living, dying, and everything in between. This opens up so many possibilities for studying ancient genomes and potentially saving endangered species 🐘💚. Can't wait to see what other cool discoveries come out of this tech! 👀
 
🐘 OMG can you believe it?! They've actually managed to get RNA from a 40k yr old mammoth 🤯 It's like, the science is insane! I mean, we thought DNA was cool, but this is on another level. The fact that they got intact fragments means we can learn so much more about how these creatures lived & died 💀 And can you imagine studying gene expression differences between extinct & living species? 🤔 It's like, totally mind-blowing! The implications are huge – maybe we can even use this tech to help endangered species? 🐯 Fingers crossed for all the good vibes 🌈
 
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