Lithium levels in drinking water 'may be linked' to higher risk of autism diagnoses, experts warn.
A recent study published in the journal JAMA Pediatrics has found a modest association between lithium exposure during pregnancy and an increased risk of autism spectrum disorder (ASD) in children. However, researchers caution that this association does not necessarily mean that lithium exposure is the direct cause of ASD.
The study examined data from over 8,800 children with ASD and more than 43,000 participants without ASD, and found that those exposed to higher levels of lithium during pregnancy had a 24% to 26% increased risk of ASD. The highest exposure group showed a 46% higher risk compared to the lowest exposure level.
While this study suggests a possible link between lithium exposure and ASD, experts emphasize that more research is needed to confirm these findings. "We need to see if there's a viable and biologically plausible mechanism by which a small amount of lithium in the water supply can somehow do this," said Dr. Beate Ritz, a co-author of the study.
Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, also expressed skepticism about the findings. "It's an interesting association, but causation is definitely not proven," he said. "We have to figure out how to safely navigate environmental stressors like this."
Other research has suggested connections between ASD and environmental exposures such as pesticides, air pollution, and phthalates. However, none of these studies have identified any single factor as a direct cause of ASD.
The implications of the study's findings are complex, and public health policy will need to carefully consider the potential risks and benefits of lithium exposure during pregnancy. Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School, noted that "if all these associations are valid, we'll need to develop guidelines for lithium in drinking water that are maximally protective of the entire population."
For now, experts urge caution and emphasize the need for further research to better understand the potential link between lithium exposure and ASD.
A recent study published in the journal JAMA Pediatrics has found a modest association between lithium exposure during pregnancy and an increased risk of autism spectrum disorder (ASD) in children. However, researchers caution that this association does not necessarily mean that lithium exposure is the direct cause of ASD.
The study examined data from over 8,800 children with ASD and more than 43,000 participants without ASD, and found that those exposed to higher levels of lithium during pregnancy had a 24% to 26% increased risk of ASD. The highest exposure group showed a 46% higher risk compared to the lowest exposure level.
While this study suggests a possible link between lithium exposure and ASD, experts emphasize that more research is needed to confirm these findings. "We need to see if there's a viable and biologically plausible mechanism by which a small amount of lithium in the water supply can somehow do this," said Dr. Beate Ritz, a co-author of the study.
Dr. Max Wiznitzer, director of the Rainbow Autism Center at University Hospitals Rainbow Babies and Children's Hospital in Cleveland, also expressed skepticism about the findings. "It's an interesting association, but causation is definitely not proven," he said. "We have to figure out how to safely navigate environmental stressors like this."
Other research has suggested connections between ASD and environmental exposures such as pesticides, air pollution, and phthalates. However, none of these studies have identified any single factor as a direct cause of ASD.
The implications of the study's findings are complex, and public health policy will need to carefully consider the potential risks and benefits of lithium exposure during pregnancy. Dr. David C. Bellinger, a professor of neurology and psychology at Harvard Medical School, noted that "if all these associations are valid, we'll need to develop guidelines for lithium in drinking water that are maximally protective of the entire population."
For now, experts urge caution and emphasize the need for further research to better understand the potential link between lithium exposure and ASD.