A new approach to a Covid-19 nasal vaccine shows early promise | CNN

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Helpful Hyena

Scientists in Germany say they've been able to create a nasal vaccine that can stop the Covid-19 virus from multiplying in the nose and throat.

In animal studies, two doses of the vaccine blocked the virus from replicating in the upper airways, producing "sterilizing immunity" and preventing illness. The researchers claim that this is a significant breakthrough as it aims to prevent Covid-19 before it can cause infection.

The German vaccine takes a new approach by weakening the coronavirus through genetic modification, making it easier for the immune system to recognize and fight it off.

While several nasal vaccines are already in use or nearing completion of clinical trials, more work needs to be done before they can be widely used.

In China and India, nasal vaccines have been rolled out but their effectiveness is still unknown due to a lack of published studies.

The US is struggling with Covid-19, with hundreds of Americans dying daily from the infection. The development of next-generation Covid-19 vaccines that induce mucosal immunity and are long-lived is crucial in halting this progress.

Research suggests that boosting mucosal immunity can prevent Covid-19 before it starts to cause illness. This approach mimics the way firefighters would respond to a fire, quickly tackling the initial outbreak.

However, experts caution that caution is warranted as more tests need to be conducted before the vaccine can be used. While the results are promising, there have been challenges in developing nasal vaccines.

At least four nasal Covid-19 vaccines are currently undergoing late-stage testing in humans, including one developed by a German team and another by Codagenix.

However, experts warn that respiratory infections have proven to be difficult targets for inhaled vaccines. The US measles vaccine, which uses live attenuated viruses, is an example of successful mucosal immunity.

Another consideration is that people with compromised immune systems may need to exercise caution when using live vaccines due to the risk of infection.
 
I'm thinking this nasal vaccine is a game changer 🤔🧬! If it can really prevent Covid-19 from taking hold in the first place, that's just huge. I mean, we've been dealing with this pandemic for years and every little breakthrough feels like a big deal 💪. But what's even more promising is that it might actually help with respiratory infections in general 🤧. The way it works by weakening the virus through genetic modification is genius 📚. And the fact that it could provide long-lasting immunity is just incredible 💥. Of course, we need to be cautious and wait for more testing, but if this thing pans out... we might finally start to see some real progress in our fight against Covid-19 🚀!
 
🤔 this breakthrough sounds like a game-changer but we gotta keep things in perspective - it's not just about creating a vaccine, its about addressing the root cause 🌱 what if we're so focused on finding quick fixes that we forget to work on our overall health & wellbeing? 💪 let's take a step back and think about the bigger picture 👀
 
🤔 Just thinking about this nasal vaccine being created in Germany... it's like they're trying to prevent the Covid-19 virus from even taking hold before it can cause any harm! 🚫💉 The idea that they've been able to "sterilize" the upper airways is mind-blowing, and it makes sense why this could be a game-changer in stopping the spread of the virus. But you're right, more work needs to be done before these vaccines can be used widely... 💯
 
🤔 I'm like super stoked about this new nasal Covid-19 vaccine in Germany!!! It's a game changer, right? They're talking about "sterilizing immunity" which means it could actually prevent Covid-19 before it even starts! That's amazing thinking on their part. And the fact that it uses genetic modification to weaken the virus is so cool (in a good way 😎). I know there are still more tests to be done, but come on, let's not focus on all the challenges... we should celebrate this breakthrough and hope it leads to even better vaccines in the future! 💪
 
Yaaas, a nasal vaccine that can stop Covid-19 from multiplying in the nose and throat? That's a game-changer, bro! 🤯 The fact that it takes a new approach by weakening the coronavirus through genetic modification is super cool. I'm all about trying out new tech and finding solutions to our problems.

I mean, think about it - this vaccine can prevent Covid-19 before it even starts causing illness? That's like having a superhero sidekick in your nose! 💪 And the fact that it induces mucosal immunity means that firefighters (or in this case, our immune systems) can tackle the initial outbreak quickly and effectively.

Of course, we need to be cautious and make sure that all the necessary tests are done before this vaccine hits the market. But from what I've seen so far, the results are promising and it's definitely something worth keeping an eye on. 💡
 
So they've made a nasal vaccine that can stop Covid from multiplying in your nose and throat? That's like a magic trick or something! 🤯 I'm not exactly sure how it works, but if it really does block the virus from replicating, that would be amazing! But what's with all these different versions of vaccines and how long do they need to test them before we can use them? I saw some news about China and India already using nasal vaccines, but we don't know much about their effectiveness yet. It's weird, I remember when Covid first started, everyone was talking about getting vaccinated, now it feels like it's been around forever! 🤷‍♀️
 
OMG this is like such amazing news!!! 🤩 Can you even imagine having a vaccine that stops Covid-19 from multiplying in your nose and throat? That would be like a game changer! 💪 I'm so excited for the German team who came up with this - they're literally saving lives here! ❤️ The fact that it's all about genetic modification makes sense, too... our bodies are so smart, and we just need to help them out sometimes. 😊 This is definitely something to be super optimistic about! 💫 Fingers crossed for everyone who needs this vaccine ASAP! 🙏
 
this is so cool! 🤯 a nasal vaccine? that sounds like something out of science fiction! i've been saying it for ages, we should have invested in more research on this from the start. what's crazy is how many nasal vaccines are already being developed and tested, but still some countries aren't sharing their results with the world. china and india need to do more transparency on this one... 🤔

i'm also thinking about the firefighters analogy, it makes total sense that boosting mucosal immunity can stop the virus from spreading so fast. like, imagine if we had a special team of 'vaccine firefighters' who could put out outbreaks before they even started? 💨

anyway, i'm definitely excited to see more progress on this front... but at the same time, i'm also worried about the challenges and risks involved. live vaccines can be tricky, especially for people with compromised immune systems... 🤕 do you guys think we'll ever see a perfect vaccine that's 100% effective? 🤔
 
🤔 I mean, yay Germany! Another country to save us all from Covid-19 🙄. A nasal vaccine that might actually work... sounds about right. We've been waiting for this for years and it's finally here. Meanwhile, China and India are over there trying their own thing without any published studies. Good luck with that 😏. And the US is just, you know, trying to keep up 🙃. Mucosal immunity, huh? Sounds like something firefighters do on a Tuesday afternoon 🔧. At least it's not as bad as those live virus vaccines... 🤮. Can't wait for more testing and, of course, caution 🙄.
 
I'm still waiting for a reliable nasal Covid-19 vaccine 🤞. I mean, it's all good and well that scientists in Germany have made some promising progress, but we can't just jump to conclusions here 💡. I've been following this story for ages, and it feels like every time we think we're getting close, there's another hurdle to overcome 🚧.

I'm not sure about the effectiveness of nasal vaccines in countries like China and India yet 🤔. We need more data on those before we can even consider them as a viable option 📊. And don't even get me started on the US – hundreds of Americans dying daily from Covid-19 is just heartbreaking 😢.

I do love the idea of boosting mucosal immunity, though 💪. It's like, imagine being able to prevent the virus from taking hold in the first place 🙏. But we need to be realistic here too 🤓. These vaccines still need to go through more testing before they can be trusted 🚫.

And have you seen the number of nasal Covid-19 vaccines that are currently in late-stage testing? Four, if I'm not mistaken 😲. It's like, how many do we really need before we start seeing some real results? 🤯
 
I don't know how some people think nasal vaccines are a new idea lol 🤦‍♀️. I mean, it's been around for years and we've known about its effectiveness in fighting respiratory infections like measles. It's not like scientists just came up with this concept out of thin air. And yeah, the German vaccine is cool and all, but let's not forget that there are already nasal vaccines being used or tested in other parts of the world, like China and India. We need to be cautious though, because we still don't have a complete understanding of how effective these vaccines are in humans yet. But honestly, it's about time someone tackled this issue head-on 🙌.
 
Im thinking we really need something like this nasal vaccine ASAP 🤞 especially in countries struggling like India and China where hospitals are still super full. I mean its promising that it can stop the virus from multiplying in the nose and throat but at the same time we gotta make sure its safe for everyone to use. Maybe a trial run before rolling it out globally? That way we can get more data on how effective it is and who should be taking it. And its also worrying when you think about people with compromised immune systems, do we need to have some kind of special precautions in place for them?
 
🌟 Can you imagine waking up one morning and not having to worry about Covid-19 anymore? 🤞 This new nasal vaccine sounds like a game-changer, especially for those who've lost loved ones or struggled with the virus. The fact that it's got "sterilizing immunity" is mind-blowing! 💥

I'm keeping my fingers crossed that this tech makes its way to the US and other countries soon, we really do need a breakthrough like this 🙏 especially with all those people still fighting the good fight against Covid. Let's keep hoping for the best and sending love to everyone who's been affected by this pandemic 💕
 
🤔 just imagine if we had a nasal vaccine like this one already 🚨💉 it would be so much easier to prevent covid-19 from taking hold in our bodies... and it's crazy that germany is leading the way on this innovation 💡 meanwhile, it's disheartening to think about all those americans suffering from covid-19 daily 😔 we need more research and testing ASAP to make these nasal vaccines available to everyone 🚀
 
I'm low-key hyped about this nasal Covid-19 vaccine in Germany 🤩! The idea of stopping the virus from multiplying in the nose and throat before it causes infection is total game-changer 💡. But, let's keep things real for a sec... We need to see more published studies on these nasal vaccines, especially in countries like China and India where they're already being rolled out 🤝.

It's also super important to acknowledge that developing next-gen Covid-19 vaccines that induce mucosal immunity is crucial in halting the spread of this virus. But, we can't just rush into it without doing more research and considering the potential risks, especially for people with compromised immune systems 🤕.
 
🤔 I'm really hopeful about this new nasal Covid-19 vaccine from Germany. It's like a game-changer for stopping the virus before it even starts to spread. I mean, imagine being able to prevent illness without having to take a full-blown vaccine... that would be huge! 💪 But at the same time, we need to remember that this is still just in animal studies and more research needs to be done. 🧬 I'm not sure if it's ready for human trials yet. And what about people with weakened immune systems? We can't afford to take any risks there. 💉 Still, I think this is a great step forward and fingers crossed that it'll make a real difference soon! 💕
 
just imagine if we had a nasal vaccine like this in our region! 🤞 it would be super convenient not having to take shots or worry about needles 🙅‍♂️ especially for younger folks who get nervous easily 💉 plus think of all those people who have weakened immune systems due to medical conditions... this could be a game changer for them too 🌟 still, gotta wait and see how it plays out in bigger human trials before we can say yay 😐
 
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